0658 Phenotypic Characterization Of Rls In African-americans
نویسندگان
چکیده
منابع مشابه
Phenotypic variance explained by local ancestry in admixed African Americans
We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds of thousands of genotyped loci across all autosomes, we used a linear mixed effects model to estimate the variance explained by local ancestry...
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APOL1 gene renal-risk variants are associated with nephropathy and CVD in African Americans; however, little is known about the circulating APOL1 variant proteins which reportedly bind to HDL. We examined whether APOL1 G1 and G2 renal-risk variant serum concentrations or lipoprotein distributions differed from nonrisk G0 APOL1 in African Americans without nephropathy. Serum APOL1 protein concen...
متن کاملPhenotypic Characterization of Juvenile Idiopathic Arthritis in African American Children.
OBJECTIVE Juvenile idiopathic arthritis (JIA) affects children of all races. Prior studies suggest that phenotypic features of JIA in African American (AA) children differ from those of non-Hispanic white (NHW) children. We evaluated the phenotypic differences at presentation between AA and NHW children enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry, and...
متن کاملDiabetes in African Americans
the excess frequency and complications from diabetes in minority populations in the United States. In 1986, a Task Force on Black and Minority Health called attention to limitations in knowledge about diabetes in minorities and the need for increased research and intervention to reduce the excess burden of diabetes in these groups. In this chapter, data on the frequency of diabetes and associat...
متن کاملDiabetes in African Americans.
African Americans have a high risk for type 2 diabetes. Genetic traits, the prevalence of obesity, and insulin resistance all contribute to the risk of diabetes in the African American community. African Americans have a high rate of diabetic complications, because of poor glycaemic control and racial disparities in health care in the USA. African Americans with diabetes may have an atypical pr...
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ژورنال
عنوان ژورنال: Sleep
سال: 2019
ISSN: 0161-8105,1550-9109
DOI: 10.1093/sleep/zsz067.656